Optimization of the extraction of phenolic compounds from Globularia alypum L. / Imane Zidelmel

Public ISBD Titre : Optimization of the extraction of phenolic compounds from Globularia alypum L. Type de document : document multimédia Auteurs : Imane Zidelmel, Auteur ; Bakhti Koribaa, Directeur de thèse Editeur : Laghouat : Université Amar Telidji - Département des sciences de la matière Année de publication : 2025 Importance : 45 p. Accompagnement : 1 disque optique numérique (CD-ROM) Note générale : Option : Organic chemistry Langues : Anglais (eng) Mots-clés : Antioxidant activity  Extraction  Optimization  Globularia alypum L  Phenolic compounds  Box behnken Résumé : In this study, we extracted polyphenols of the plant Globularia alypum L using ultrasonic extraction process. The use of Response surface Methodology multivariate method by Box-Behnken design allows us to optimize three variables (temperature, time and volume of methanol). In order to obtain the best yield of Total Phenolic Compounds TPC;as well as the best antioxidants activities for both DPPH and ABTS. The optimal TPC yield was observed at 45 °C, 20 min, and 35 mL, while maximum antioxidant activities for both DPPH and ABTS occurred near 50 °C and 25 min. A strong correlation was observed between TPC and DPPH activities, confirming the contribution of phenolic compounds to radical scavenging potential. ABTS showed a similar but slightly weaker correlation. Overall, these results highlight the importance of optimizing extraction parameters to maximize the recovery of bioactive phenolics and their associated antioxidant activities. note de thèses : Mémoire de master en chimie Optimization of the extraction of phenolic compounds from Globularia alypum L. [document multimédia] / Imane Zidelmel, Auteur ; Bakhti Koribaa, Directeur de thèse . - Laghouat : Université Amar Telidji - Département des sciences de la matière, 2025 . - 45 p. + 1 disque optique numérique (CD-ROM). Option : Organic chemistry Langues : Anglais (eng) Mots-clés : Antioxidant activity  Extraction  Optimization  Globularia alypum L  Phenolic compounds  Box behnken Résumé : In this study, we extracted polyphenols of the plant Globularia alypum L using ultrasonic extraction process. The use of Response surface Methodology multivariate method by Box-Behnken design allows us to optimize three variables (temperature, time and volume of methanol). In order to obtain the best yield of Total Phenolic Compounds TPC;as well as the best antioxidants activities for both DPPH and ABTS. The optimal TPC yield was observed at 45 °C, 20 min, and 35 mL, while maximum antioxidant activities for both DPPH and ABTS occurred near 50 °C and 25 min. A strong correlation was observed between TPC and DPPH activities, confirming the contribution of phenolic compounds to radical scavenging potential. ABTS showed a similar but slightly weaker correlation. Overall, these results highlight the importance of optimizing extraction parameters to maximize the recovery of bioactive phenolics and their associated antioxidant activities. note de thèses : Mémoire de master en chimie

Réservation

Réserver ce document

Exemplaires (1)

Code-barres	Cote	Support	Localisation	Section	Disponibilité
MC 01-111	MC 01-111	CD	BIBLIOTHEQUE DE FACULTE DES SCIENCES	théses (sci)	Disponible

---

1 (1 - 1 / 1) Par page : 25 50 100 200