Titre :	Combinatorial effect of plant-honeys on preventing the gou desease : an in vitro study
Type de document :	document multimédia
Auteurs :	Ilyes Mohamed El Amine Yabrir, Auteur ; Amar Djeridane, Directeur de thèse ; Chahrazed Hamia, Directeur de thèse
Editeur :	Laghouat : Université Amar Telidji - Département des sciences de la matière
Année de publication :	2025
Importance :	40 p.
Accompagnement :	1 disque optique numérique (CD-ROM)
Note générale :	Option : Organic chemistry
Langues :	Anglais
Mots-clés :	Laurus nobilis  Rosmarinus officinalis  Honey  Combination  Extract xanthine oxidase  Uric acid  Toxicity  protein degradation
Résumé :	This laboratory study aimed to evaluate the effectiveness of 12 extracts issued of binary combination of two medicinal plants and six local honeys as inhibitors of xanthine oxidase, protein hydrolysis, and uric acid dissolution. It also evaluated their effect on red blood cells, as well as examined some phytochemical compounds. The analysis showed that there were monumental differences in the content of phenolic compounds and mineral salts according to the plant and honey species. The experiments revealed that all the extracts possessed varying degrees of anti-gout action. The best was Laurus nobilis and Rosmarinus officinalis (two honeys). They presented the strongest inhibition of xanthine oxidase and highest ability to dissolve uric acid. However, it has been noted that Laurus nobilis extract is harmful to red blood cells, as compared to Rosmarinus officinalis, thus making it a safer molecule for the therapeutic treatment of diseases caused by this enzyme.
note de thèses :	Mémoire de master en chimie

Combinatorial effect of plant-honeys on preventing the gou desease : an in vitro study [document multimédia] / Ilyes Mohamed El Amine Yabrir, Auteur ; Amar Djeridane, Directeur de thèse ; Chahrazed Hamia, Directeur de thèse . - Laghouat : Université Amar Telidji - Département des sciences de la matière, 2025 . - 40 p. + 1 disque optique numérique (CD-ROM).
Option : Organic chemistry
Langues : Anglais

Mots-clés :	Laurus nobilis  Rosmarinus officinalis  Honey  Combination  Extract xanthine oxidase  Uric acid  Toxicity  protein degradation
Résumé :	This laboratory study aimed to evaluate the effectiveness of 12 extracts issued of binary combination of two medicinal plants and six local honeys as inhibitors of xanthine oxidase, protein hydrolysis, and uric acid dissolution. It also evaluated their effect on red blood cells, as well as examined some phytochemical compounds. The analysis showed that there were monumental differences in the content of phenolic compounds and mineral salts according to the plant and honey species. The experiments revealed that all the extracts possessed varying degrees of anti-gout action. The best was Laurus nobilis and Rosmarinus officinalis (two honeys). They presented the strongest inhibition of xanthine oxidase and highest ability to dissolve uric acid. However, it has been noted that Laurus nobilis extract is harmful to red blood cells, as compared to Rosmarinus officinalis, thus making it a safer molecule for the therapeutic treatment of diseases caused by this enzyme.
note de thèses :	Mémoire de master en chimie